Synbiotic containing extensively hydrolyzed formula improves gastrointestinal and atopic symptom severity, growth, caregiver quality of life, and hospital‐related healthcare use in infants with cow's milk allergy

Autor: Gary P. Hubbard, Kiranjit Atwal, Lynne Graham, Sankara Narayanan, Lisa Cooke, Catherine Casewell, Sally‐Ann Denton, Joan Gavin, Robert M. Browne, Fiona J. Kinnear, Ailsa J. McHardy, Debbie Evans, Rachel Vallis, Devasmitha Venkataraman, Abbie L. Cawood, Sarah Donohoe, Victoria Steele, Sonia Armstrong, Rebecca J. Stratton
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Immunity, Inflammation and Disease, Vol 10, Iss 6, Pp n/a-n/a (2022)
Druh dokumentu: article
ISSN: 2050-4527
DOI: 10.1002/iid3.636
Popis: Abstract Background Healthy gut microbiota is important for prognosis in cow's milk allergy (CMA). The application of synbiotics (specific pre‐ and probiotics) in extensively hydrolyzed formulae (eHFs) is a relatively new concept. Aims To evaluate a synbiotic‐containing, whey‐based eHF (SeHF) with galacto‐oligosaccharides, fructo‐oligosaccharides, and bifidobacterium breve M‐16V in infants with CMA. Materials and Methods A 31‐day one‐arm pilot study in 29 infants with CMA (mean age 30.8 weeks [SD 11]) was undertaken, with outcomes including gastrointestinal tolerance, atopic dermatitis symptoms, dietary intake, growth, SeHF acceptability, caregiver quality of life, and hospital‐related healthcare use. Results Significant improvements (p
Databáze: Directory of Open Access Journals
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