Is dynamic thiol/disulfide homeostasis associated with the prognosis of myelodysplastic syndrome?
| Autor: | Ali Ucar Mehmet, Tombak Anıl, Dagdas Simten, Akdeniz Aydan, Ceran Funda, Neselioglu Salim, Erel Ozcan, Ozet Gulsum |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Journal of Medical Biochemistry, Vol 39, Iss 3, Pp 336-345 (2020) |
| Druh dokumentu: | article |
| ISSN: | 1452-8258 1452-8266 |
| Popis: | Background: This study planned to investigate the relationship of dynamic thiol/disulfide homeostasis with the prognosis of myelodysplastic syndrome (MDS). Methods: 80 patients who had been diagnosed with MDS between 2012 and 2017 and who were older than 18 were included in the study together with 80 healthy control subjects. The MDS diagnosis was confirmed using bone marrow aspiration-biopsy immunostaining. Dynamic thiol/disulfide homeostasis and ischemia-modified albumin (IMA) levels were examined. Results: The average IMA (0.71±0.08 vs. 0.67±0.09; p=0.002), median disulfide (18.0 vs. 11.6; p |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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