Improved survival with radiotherapy in hepatocellular carcinoma with major vascular invasion: A propensity‐matched analysis of Surveillance, Epidemiology, and End Results database

Autor:	Qiuyan Lin, Xiaoquan Huang, Canmei Zhong, Tiancheng Luo, Xiaoqing Zeng, Shiyao Chen
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	hepatocellular carcinoma major vascular invasion propensity score‐match radiotherapy Surveillance Epidemiology Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Cancer Medicine, Vol 8, Iss 2, Pp 515-526 (2019)
Druh dokumentu:	article
ISSN:	2045-7634
DOI:	10.1002/cam4.1937
Popis:	Abstract Objectives Hepatocellular carcinoma (HCC) associated with major vascular invasion is an advanced stage disease with an extremely poor prognosis and low survival rate. Our study evaluated the survival benefit of radiotherapy (RT) in HCC patients with major vascular invasion through Surveillance, Epidemiology, and End Results database. Methods We analyzed 3181 HCC patients with major vascular invasion cases diagnosed from 2004 to 2013. Patients (N = 308) who underwent RT and patients (N = 2873) who did not receive RT were compared. We successfully analyzed patients using propensity score matching (PSM). Kaplan‐Meier and Cox‐regression analyses were applied to assess prognosis. Results The median survival time in radiation‐treated group was longer compared to the control group (7 months vs 3 months; P
Databáze:	Directory of Open Access Journals
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