Serological profile of hepatitis B in children after the introduction of its vaccination in Burkina Faso
| Autor: | Makoura Barro, Diane Valea, Saga Alain Ouermi, Sanata Sessouma, Bintou Sanogo, Ibrahim Ad Bafa Ouattara, Abdoul Salam Ouedraogo, Boubacar Nacro, Georges Moyen |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Pediatric Reports, Vol 11, Iss 4 (2019) |
| Druh dokumentu: | article |
| ISSN: | 2036-749X 2036-7503 |
| DOI: | 10.4081/pr.2019.8248 |
| Popis: | Viral hepatitis B is a public health issue. We establish the children serological profile of hepatitis B in Bobo-Dioulasso, six years after the introduction of hepatitis B vaccine into the Expanded Program on Immunization. This was a descriptive study of prospective data collection carried out in the Department of Pediatrics and the laboratory of virology of the Centre MURAZ of Bobo-Dioulasso between March 2013 and May 2013. Blood samples were made in search of the following hepatitis B serological markers: anti-HBcAb total, HBsAg, Ac anti-HBs, HBeAg, AcHBs, IgM anti-HBc total. The ELISA method with the Monolisa BIORAD reagents was used. A total of 2015 children were included, 1026 (50, 9%) boys and 989 (49.1%) girls, at an average age of 58±48 months. Out of these 2015 children, 53 (2.6%) were positive to HBsAg including 19 vaccinated cases, one child has received 3 doses plus 1 booster dose of hepatitis B vaccine. We found no statistically significant difference in the carriage of serologic markers of hepatitis B between the unvaccinated group and the vaccinated group. Large-scale studies should be carried out in Burkina Faso to see the real impact of vaccination on the health of our populations. |
| Databáze: | Directory of Open Access Journals |
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