| Autor: |
Chih-Jung Chen, Ping-Ing Lee, Shih-Cheng Chang, Yhu-Chering Huang, Cheng-Hsun Chiu, Yu-Chia Hsieh, Shang-Chwen Chang, Feng-Yee Chang, Jen-Jyh Lee, Shey-Chiang Su, Gwan-Han Shen, Yin-Ching Chuang, Yao-Shen Chen, Jien-Wei Liu, Tzou-Yien Lin |
| Jazyk: |
angličtina |
| Rok vydání: |
2011 |
| Předmět: |
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| Zdroj: |
PLoS ONE, Vol 6, Iss 9, p e24440 (2011) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0024440 |
| Popis: |
BACKGROUND: This study is to determine the seroprevalence of the pandemic influenza A H1N1 virus (pH1N1) in Taiwan before and after the 2009 pandemic, and to estimate the relative severity of pH1N1 infections among different age groups. METHODOLOGY/PRINCIPAL FINDINGS: A total of 1544 and 1558 random serum samples were collected from the general population in Taiwan in 2007 and 2010, respectively. Seropositivity was defined by a hemagglutination inhibition titer to pH1N1 (A/Taiwan/126/09) ≥1:40. The seropositivity rate of pH1N1 among the unvaccinated subjects and national surveillance data were used to compare the proportion of infections that led to severe diseases and fatalities among different age groups. The overall seroprevalence of pH1N1 was 0.91% (95% confidence interval [CI] 0.43-1.38) in 2007 and significantly increased to 29.9% (95% CI 27.6-32.2) in 2010 (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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