| Autor: |
Wen Zhou, Lijuan Han, Sayed Haidar Abbas Raza, Qingming Yue, Shengnan Sun, Yuxin Zhao, Lifei Lv, Yongrong Deng, Zhenzhen Yuan, Ifat Alsharif, Zuhair M Mohammedsaleh, Fatima S. Alaryani, Mashael Alhumaidi Alotaibi, Raed Albiheyri, Faisal Al-Sarraj, Mohammed Hasan Mukhtar |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Journal of Functional Foods, Vol 100, Iss , Pp 105381- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1756-4646 |
| DOI: |
10.1016/j.jff.2022.105381 |
| Popis: |
This study investigated the effects of ultra-filtered polysaccharides from Berberis dasystachya Maxim. (UBDP) on the gut microbiota and glucose metabolism in high-fat diet/streptozotocin -induced diabetic rats, and clarified the possible action mechanisms of UBDP in the treatment of type 2 diabetes mellitus (T2DM). The results showed that UBDP administration for 4 weeks significantly ameliorated glucose tolerance, improved organ function, reduced fasting blood glucose and HbA1c levels, decreased the glycosylated hemoglobin index, improved insulin sensitivity of the pancreas, and reduced colon morphogen and oxidative stress in the diabetic rats (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
Full Text from ScienceDirect