Autor: |
ZHAO Lei, LI Ruqiang, YUAN Mingxia |
Jazyk: |
čínština |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Zhongguo quanke yixue, Vol 25, Iss 09, Pp 1113-1118 (2022) |
Druh dokumentu: |
article |
ISSN: |
1007-9572 |
DOI: |
10.12114/j.issn.1007-9572.2021.02.128 |
Popis: |
BackgroundCardiac autonomic neuropathy (CAN) is a common and severe chronic diabetic complication, whose association with thyroid function has rarely been reported.ObjectiveTo investigate the association between subclinical hypothyroidism and CAN in type 2 diabetes mellitus (T2DM) .MethodsWe performed a retrospective analysis of 564 outpatients and hospitalized patients with T2DM recruited from Beijing Friendship Hospital, Capital Medical University from October 2019 to October 2020. Baseline characteristics, physical and laboratory examination results were collected. Ewing test was performed to identify CAN. The association between subclinical hypothyroidism and CAN was assessed using the Pearson correlation coefficient and Spearman's rank coefficient of correlation. Factors associated with CAN in T2DM were identified using multivariate, stepwise logistic regression.ResultsOne hundred and twenty-nine subjects (22.9%) were found with CAN, and other 435 without. Subclinical hypothyroidism was detected in 84 cases (14.9%) , including 36 with CAN and 48 without. The prevalence of subclinical hypothyroidism in those with CAN〔28.0% (36/129) 〕 was higher than that of those without〔11.0% (48/435) 〕 (χ2=22.346, P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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