Risk factors associated with glycated hemoglobin A1c trajectories progressing to type 2 diabetes

Autor: Alexandra Halalau, Sujoy Roy, Arpitha Hegde, Sumesh Khanal, Emily Langnas, Maidah Raja, Ramin Homayouni
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Annals of Medicine, Vol 55, Iss 1, Pp 371-378 (2023)
Druh dokumentu: article
ISSN: 07853890
1365-2060
0785-3890
DOI: 10.1080/07853890.2022.2164347
Popis: AbstractBackground and objective The notion of prediabetes, defined by the ADA as glycated hemoglobin A1c (HbA1c) of 5.7–6.4%, implies increased vascular inflammatory and immunologic processes and higher risk for developing diabetes mellitus and major cardiovascular events. We aimed to determine the risk factors associated with rapid progression of normal and prediabetes patients to type 2 diabetes mellitus (T2DM).Methods Retrospective cohort study in a single 8-hospital health system in southeast Michigan, between 2006 and 2020. All patients with HbA1c
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