Autor: |
Gary M Hunninghake, Zachary S Wallace, Edwin K Silverman, George R Washko, Jeffrey A Sparks, Michael H Cho, Matthew Moll, Pierre-Antoine Juge, Elizabeth A Regan, Raul San Jose Estepar, Gregory L Kinney, Paul F Dellaripa, Samuel Y Ash, Keigo Hayashi, Tracy J Doyle, Xiaosong Wang, Misti L Paudel, Gregory C McDermott, Danielle Sansone-Poe, Kendra Young |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
RMD Open, Vol 10, Iss 2 (2024) |
Druh dokumentu: |
article |
ISSN: |
2056-5933 |
DOI: |
10.1136/rmdopen-2024-004281 |
Popis: |
Objective To compare longitudinal changes in spirometric measures between patients with rheumatoid arthritis (RA) and non-RA comparators.Methods We analysed longitudinal data from two prospective cohorts: the UK Biobank and COPDGene. Spirometry was conducted at baseline and a second visit after 5–7 years. RA was identified based on self-report and disease-modifying antirheumatic drug use; non-RA comparators reported neither. The primary outcomes were annual changes in the per cent-predicted forced expiratory volume in 1 s (FEV1%) and per cent predicted forced vital capacity (FVC%). Statistical comparisons were performed using multivariable linear regression. The analysis was stratified based on baseline smoking status and the presence of obstructive pattern (FEV1/FVC |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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