CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion

Autor: Zhiqian Li, Nimi Marcel, Sushil Devkota, Ankush Auradkar, Stephen M. Hedrick, Valentino M. Gantz, Ethan Bier
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-22927-1
Popis: CRISPR-based genetic elements can copy themselves across host genomes. Here the authors introduce CopyCatcher, a gene-drive related system for detecting and quantifying somatic gene conversion events.
Databáze: Directory of Open Access Journals