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AIM: To analyze and compare the effect of femtosecond laser micro-incision corneal stromal lens excision(SMILE)and excimer laser in situ keratomileusis(LASIK)in the treatment of myopia after operation, to explore the safety, operability and prediction of SMILE. METHODS: In this prospective clinical controlled study, 100 cases(200 eyes)received SMILE and 100 cases(200 eyes)undergone LASI in our hospital in the same period were selected. Uncorrected visual acuity, diopter, corrected visual acuity, slit lamp examination, intraocular pressure and corneal anterior segment OCT, corneal topography(Obscan II)of two groups in 1d, 1wk, 1, 3, 6mo, 1a were compared. Independent samples t test was used for data analysis. RESULTS: 1)Postoperative slit lamp examination: after 1d in SMILE group, there were less eyes had corneal layer between mild cloudy or edema; postoperative 1wk corneal layer disappeared, cornea became clear and transparent. 2)Postoperative vision recovery: 1d after operation, vision recovery in LASIK group was better than that in SMILE group, the difference was statistically significant(PP>0.05). 3)Obscan II examination: graphics in the SMILE group was more regular and placed in the center, no eccentric and irregular graphics, better than that in the LASIK group. 4)Anterior segment OCT examination: postoperative corneal flap in the SMILE group was more uniform and accurate, but it was thin in the center and slightly thick the peripheral part in the LASIK groups. 5)Postoperative visual quality assessment used subjective questionnaire survey. The two groups had statistically significant difference on 4 points and 1 points(PCONCLUSION: SMILE is safe, effective, stable and predictable for the correction of myopia. |
