Analysis of the association between the LUM rs3759223 variant and high myopia in a Japanese population
| Autor: | Okui S, Meguro A, Takeuchi M, Yamane T, Okada E, Iijima Y, Mizuki N |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Clinical Ophthalmology, Vol Volume 10, Pp 2157-2163 (2016) |
| Druh dokumentu: | article |
| ISSN: | 1177-5483 33692645 |
| Popis: | Shintaro Okui,1 Akira Meguro,1 Masaki Takeuchi,1,2 Takahiro Yamane,1 Eiichi Okada,3 Yasuhito Iijima,4 Nobuhisa Mizuki1 1Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan; 2Inflammatory Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA; 3Okada Eye Clinic, Yokohama, Kanagawa, Japan; 4Aoto Eye Clinic, Yokohama, Kanagawa, Japan Purpose: Many studies have investigated the relationship of the lumican gene (LUM) rs3759223 variant with the risk of high myopia, but the results have been inconsistent and inconclusive. In this study, we investigated whether LUM rs3759223 is associated with high myopia in a Japanese population.Methods: We recruited 1,585 Japanese patients with high myopia (spherical equivalent [SE] |
| Databáze: | Directory of Open Access Journals |
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