Hydrophilic Surface Modification of PDMS Microchannel for O/W and W/O/W Emulsions

Autor: Shazia Bashir, Muhammad Bashir, Xavier Casadevall i Solvas, Julia M. Rees, William B. Zimmerman
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Micromachines, Vol 6, Iss 10, Pp 1445-1458 (2015)
Druh dokumentu: article
ISSN: 2072-666X
DOI: 10.3390/mi6101429
Popis: A surface modification method for bonded polydimethylsiloxane (PDMS) microchannels is presented herein. Polymerization of acrylic acid was performed on the surface of a microchannel using an inline atmospheric pressure dielectric barrier microplasma technique. The surface treatment changes the wettability of the microchannel from hydrophobic to hydrophilic. This is a challenging task due to the fast hydrophobic recovery of the PDMS surface after modification. This modification allows the formation of highly monodisperse oil-in-water (O/W) droplets. The generation of water-in-oil-in-water (W/O/W) double emulsions was successfully achieved by connecting in series a hydrophobic microchip with a modified hydrophilic microchip. An original channel blocking technique to pattern the surface wettability of a specific section of a microchip using a viscous liquid comprising a mixture of honey and glycerol, is also presented for generating W/O/W emulsions on a single chip.
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