Clinical significance of prognostic nutritional index (PNI)-monocyte-to-lymphocyte ratio (MLR)-platelet (PLT) score on postoperative outcomes in non-metastatic clear cell renal cell carcinoma

Autor: Wenming Ren, Hao Zhang, Li Cheng, Yu Zhang, Chenglin Yang, Liang Nie, Congcong Yang, Peng Yao, Jie Han, Dong Zhuo
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Surgery, Vol 23, Iss 1, Pp 1-13 (2023)
Druh dokumentu: article
ISSN: 1471-2482
DOI: 10.1186/s12893-023-02001-x
Popis: Abstract Background Prognositic nutritional index (PNI), monocyte-to-lymphocyte ratio (MLR) and platelet (PLT) are associated with tumor survival in many human malignancies. Whereas, no study combined PNI-MLR-PLT score and indicated its predictive significance on the prognosis of patients with non-metastatic clear cell renal cell carcinoma (ccRCC). Methods In this study, we retrospectively collected the clinicopathological characteristics and prognostic data from 164 cases of non-metastatic ccRCC and aimed to determine the clinical significance of PNI-MLR-PLT score on patients’ outcomes after surgery. The optimal cut-off values of PNI (PNI > 47.40 vs PNI 0.31 vs MLR 245 vs PLT
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