| Autor: |
Michael Bodnar, Ashok K. Malla, Carolina Makowski, M. Mallar Chakravarty, Ridha Joober, Martin Lepage |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
BJPsych Open, Vol 2, Pp 139-146 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2056-4724 |
| DOI: |
10.1192/bjpo.bp.115.002444 |
| Popis: |
BackgroundCurrent neuroscience literature has related treatment with aripiprazole to improved memory performance and subcellular changes in the hippocampus.AimsTo explore the volumetric changes in hippocampal grey matter in people with a first episode of psychosis (FEP) treated with second-generation antipsychotics.MethodBaseline and 1-year follow-up magnetic resonance images were obtained. Hippocampal volumes were estimated by using FreeSurfer and MAGeT-Brain. Subgroups included: aripiprazole (n=13), olanzapine (n=12), risperidone/paliperidone (n=24), refused-antipsychotics (n=13) and controls (n=44).ResultsAripiprazole subgroup displayed significant increases in bilateral hippocampal volume compared with all other subgroups (FreeSurfer: all P's |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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