Oxford-MEST classification in IgA nephropathy patients: A report from Iran
| Autor: | Hamid Nasri, Mojgan Mortazavi, Ali Ghorbani, Heshmatollah Shahbazian, Soleiman Kheiri, Azar Baradaran, Afsoon Emami-Naieni, Maryam Saffari, Saeed Mardani, Ali Momeni, Yahya Madihi, Milad Baradaran-Ghahfarokhi, Mahmoud Rafieian-Kopaie, Parin Hedayati, Shahzad Baradaran, Mohammadreza Ardalan, Shahram Sajjadieh, Naziheh Assarzadegan, Seyed Mohammad Ahmadi Soleimani, Mohamad Reza Tamadon |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Journal of Nephropathology, Vol 1, Iss 1, Pp 31-42 (2012) |
| Druh dokumentu: | article |
| ISSN: | 2251-8363 2251-8819 |
| DOI: | 10.5812/jnp.7 |
| Popis: | Background: There is a limited knowledge about the morphological features of IgA nephropathy (IgAN)in the middle east region. Objectives: The objective of this study was to evaluate the spectrum of histopathological findings in IgAN patients at our laboratory. Patients and Methods: At this work, an observational study reported which was conducted on IgAN patients using the Oxford-MEST classification system. Results: In this survey, of 102 patients 71.6 % were male. The mean age of the patients was 37.7 ± 13.6 years. Morphologic variables of MEST classification was as follows; M1: 90.2 %, E: 32 %, S: 67 % also,T in grads I and II were in 30% and 19% respectively, while 51% were in grade zero. A significant difference was observed in segmental glomerulosclerosis (P=0.003) and interstitial fibrosis/tubular atrophy frequency distribution (P= 0.045), between males and females . Furthermore, it was found that mesangial hypercellularity was more prevalent in yonger patients. Moreover, there was a significant correlation between serum creatinine and crescents (P |
| Databáze: | Directory of Open Access Journals |
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