Comparing breath hold versus free breathing irradiation for left-sided breast radiotherapy by PlanIQ™

Autor: Ke Yuan, Xinghong Yao, Xiongfei Liao, Pen Diao, Xin Xin, Jiabao Ma, Jie Li, Lucia Clara Orlandini
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Radiation Oncology, Vol 18, Iss 1, Pp 1-8 (2023)
Druh dokumentu: article
ISSN: 1748-717X
DOI: 10.1186/s13014-023-02386-2
Popis: Abstract Background Breast cancer is the most widespread cancer in women and young women worldwide. Moving towards customised radiotherapy, balancing the use of the available technology with the best treatment modality may not be an easy task in the daily routine. This study aims to evaluate the effectiveness of introducing IQ-feasibility into clinical practice to support the decision of free-breathing (FB) versus breath-hold (BH) left-sided breast irradiations, in order to optimise the technology available and the effectiveness of the treatment. Methods Thirty-five patients who received 3D radiotherapy treatment of the left breast in deep-inspiration BH were included in this retrospective study. Computed tomography scans in FB and BH were acquired for each patient; targets contoured in both imaging datasets by an experienced radiation oncologist, and organs at risk delineated using automatic segmentation software were exported to PlanIQ™ (Sun Nuclear Corp.) to generate feasibility dose volume histogram (FDVHs). The dosimetric parameter of BH versus FB FDVH, and BH clinical dataset versus BH FDVH were compared. Results A total of 30 patients out of 35 patients analysed, presented for the BH treatments a significant reduction (p
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