A community-based intervention to decrease the prevalence of HIV viremia among people who inject drugs in Vietnam

Autor: Huong Thi Duong, Jean-Pierre Moles, Khue Minh Pham, Roselyne Vallo, Giang Thi Hoang, Vinh Hai Vu, Oanh Thi Hai Khuat, Thanh Tuyet Thi Nham, Duc Quang Nguyen, Catherine Quillet, Delphine Rapoud, Philippe Van de Perre, Joëlle Castellani, Jonathan Feelemyer, Laurent Michel, Didier Laureillard, Don Des Jarlais, Nicolas Nagot
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: The Lancet Regional Health. Western Pacific, Vol 27, Iss , Pp 100538- (2022)
Druh dokumentu: article
ISSN: 2666-6065
DOI: 10.1016/j.lanwpc.2022.100538
Popis: Summary: Background: In most low-to-middle-income countries, HIV control at the population level among people who inject drugs (PWID) remains a major challenge. We aimed to demonstrate that an innovative intervention can identify HIV-positive PWID in the community who are not treated efficiently, and get them treated efficiently. Methods: Between 2016 and 2020, we implemented an intervention consisting of mass HIV screening of PWID using three annual respondent-driven sampling surveys (RDSS) and a post-intervention evaluation RDSS in community-based organisation (CBO) sites, coupled with peer support to facilitate/improve access to antiretroviral and methadone therapy in Haiphong, Vietnam. The primary outcome was the proportion of identified uncontrolled HIV-positive PWID who achieved viral control. We also estimated the potential effect of the intervention on the proportion of PWID with HIV RNA >1000 copies/mL among all PWID during the study period. Findings: Over the three RDSS, 3150 different PWID were screened, i.e. two-thirds of the estimated population size. They all injected heroin, their median age was of 39 years, 95% were male, 26.5% were HIV-infected, and 78.6% of the latter had HIV RNA ≤1000 copies/mL. Among the 177 PWID identified with an unsuppressed viral load, 73 (41.2%) achieved viral suppression at the final visit. HIV viremia decreased from 7.2% at baseline to 2.9% at the final RDSS (p
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