Effects of septal myectomy on left atrial and left ventricular function in obstructive hypertrophic cardiomyopathy

Autor: Kyung Eun Ha, Kang‐Un Choi, Hee‐Jung Lee, Seo‐Yeon Gwak, Kyu Kim, Iksung Cho, Geu‐Ru Hong, Jong‐Won Ha, Chi Young Shim
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: ESC Heart Failure, Vol 10, Iss 5, Pp 2939-2947 (2023)
Druh dokumentu: article
ISSN: 2055-5822
DOI: 10.1002/ehf2.14481
Popis: Abstract Aims Mechanical function of the left atrium (LA) and the left ventricle (LV) has been demonstrated to be a prognostic factor in patients with hypertrophic cardiomyopathy (HCM). We explore whether myocardial mechanical function can be improved by septal reduction therapy in symptomatic obstructive HCM. Methods and results Among 65 patients who underwent septal myectomy for symptomatic obstructive HCM from 2006 to 2022, 44 were analysed after excluding those who underwent simultaneous valve repair or replacement or maze operation. LA and LV functional variables including LA strain and LV global longitudinal strain were evaluated by two‐dimensional and speckle‐tracking echocardiography and compared before and 1 year after surgery. After septal myectomy, LA volume index (58.1 ± 18.3 vs. 45.3 ± 14.6 mL/m2, P = 0.001) decreased significantly. As LV end‐systolic dimension increased after surgery, the LV ejection fraction decreased (73.8 ± 6.7 vs. 62.9 ± 8.3%, P
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