ANTIOXIDANT NAPHTHOQUINONES OF Sinningia reitzii FROM SANTA CATARINA STATE, BRAZIL

Autor: Vanessa Winiewski, Adson S. Silva, Kattleen D. C. Alvarez, Eduardo L. de Sá, Marcos J. Salvador, Maria Élida A. Stefanello
Jazyk: English<br />Spanish; Castilian<br />Portuguese
Rok vydání: 2021
Předmět:
Zdroj: Química Nova, Vol 44, Iss 3, Pp 284-287 (2021)
Druh dokumentu: article
ISSN: 1678-7064
0100-4042
DOI: 10.21577/0100-4042.20170682
Popis: Sinningia reitzii (Hoehne) L. E. Skog (Gesneriaceae) is a subshrub native to Brazil, where it is distributed in two disjunctive populations around the 26°S and 23°S parallels. In this work, tubers of plants from the wild population growing at the 26°S parallel (Santa Catarina state) yielded two new naphthoquinones, 5,6-dihydroxy-7-methoxy-a-dunnione and 8-hydroxy-6,7-dimethoxy-a-dunnione. Three known compounds were also isolated: 6,8-dihydroxy-7-methoxy-a-dunnione, 5-hydroxy-6,7-dimethoxy-a-dunnione, and 6,8-dihydroxy-7-methoxy-2-O-methyldunniol. The naphthoquinones 6,8-dihydroxy-7-methoxy-2-O-methyldunniol, 6,8-dihydroxy-7-methoxy-a-dunnione, and 5,6-dihydroxy-7-methoxy-a-dunnione displayed antioxidant activity in the ORAC-FL method, with values of relative trolox equivalent in the range of 1.39-4.83 mmol g-1.
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