Selecting DCD Recipients Using Predictive Indices
| Autor: | Saif Ganni, Greta Handing, BS, Adrish Anand, BS, Spencer Barrett, BS, Nhu Thao Nguyen Galvan, MD, MPH, Christine O’Mahony, MD, John A. Goss, MD, Ronald T. Cotton, MD, FACS, Abbas Rana, MD, FACS |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Transplantation Direct, Vol 9, Iss 4, p e1467 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2373-8731 00000000 |
| DOI: | 10.1097/TXD.0000000000001467 |
| Popis: | Background. Donation after circulatory death (DCD) allografts might represent one of the largest untapped sources of liver allografts. Our aim was to identify independent recipient risk factors that predict mortality in DCD allograft recipients to preselect optimal candidates for successful transplantation. Furthermore, we compared the application of our newly constructed DCD Recipient Selector Index (RSI) score to previously developed models to determine superiority in predicting recipient survival. Methods. Using the Organ Procurement and Transplantation Network database, we performed univariate and multivariate retrospective analyses on 4228 DCD liver allograft recipients. Results. We identified 8 significant factors and incorporated them into the weighted RSI to predict 3-mo survival following DCD liver transplantation with a C-statistic of 0.6971. The most significant recipient risk factors were recipient serum sodium levels >150 mEq/L at transplant, recipient albumin |
| Databáze: | Directory of Open Access Journals |
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