Tuberculosis preventive therapy (TPT) to prevent tuberculosis co-infection among adults with HIV-associated cryptococcal meningitis: A clinician’s perspective

Autor: John Kasibante, Morris K. Rutakingirwa, Enock Kagimu, Kenneth Ssebambulidde, Jayne Ellis, Lillian Tugume, Edward Mpoza, Fiona Cresswell, David B. Meya
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, Vol 20, Iss , Pp 100180- (2020)
Druh dokumentu: article
ISSN: 2405-5794
DOI: 10.1016/j.jctube.2020.100180
Popis: As part of the END TB strategy, the World Health organization (WHO) recommends provision of tuberculosis preventive therapy (TPT) to all people at high risk of developing active TB disease. Patients with HIV-associated cryptococcal meningitis are severely immunocompromised and therefore should be eligible for TPT. In this commentary we discuss the challenges associated with starting tuberculosis preventive therapy in patients with HIV associated cryptococcal meningitis in a clinical setting, we highlight the benefit, existing gaps and research opportunities of tuberculosis preventive therapy in this patient population.
Databáze: Directory of Open Access Journals