Current debates and advances in tick microbiome research

Autor: Alejandra Wu-Chuang, Adnan Hodžić, Lourdes Mateos-Hernández, Agustín Estrada-Peña, Dasiel Obregon, Alejandro Cabezas-Cruz
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Current Research in Parasitology and Vector-Borne Diseases, Vol 1, Iss , Pp 100036- (2021)
Druh dokumentu: article
ISSN: 2667-114X
DOI: 10.1016/j.crpvbd.2021.100036
Popis: The main importance of ticks resides in their ability to harbor pathogens that can be transmitted to terrestrial vertebrates including humans. Recently, studies have focused on the taxonomic and functional composition of the tick microbiome, its microbial diversity and variation under different factors including tick species, sex, and environment among others. Of special interest are the interactions between the tick, the microbiome and pathogens since tick microbiome can influence pathogen colonization within the tick vector, and potentially, transmission to the vertebrate host. In this review, we tackled a synthesis on the growing field of tick microbiomes. We focus on the current state of tick microbiome research, addressing controversial and hotly debated topics and advances in the precise manipulation of tick microbiome. Furthermore, we discuss the innovative anti-tick microbiota vaccines as a possible tool for microbiome modulation and thus, control of tick-borne diseases. Deciphering tick-microbiome pathogen interactions can spur new strategies to control tick-borne diseases via modulation of tick microbiome.
Databáze: Directory of Open Access Journals