Use of downstream stress imaging tests for risk stratification of patients presenting to the emergency department with chest pain and low HEART score

Autor: Rodrigo Bagur, Nikolaos Tzemos, Rami M Abazid, Cigdem Akincioglu, Yves Bureau, Maged Elrayes, Sameh Awadallah, Mohamed M Ibrahim, Amer Alaref, Nilkanth Patil
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Open Heart, Vol 11, Iss 2 (2024)
Druh dokumentu: article
ISSN: 2053-3624
DOI: 10.1136/openhrt-2024-002735
Popis: Background Patients with low HEART (History, Electrocardiogram, Age, Risk factors, and Troponin level) risk scores who are discharged from the emergency department (ED) may present clinical challenges and diagnostic dilemmas. The use of downstream non-invasive stress imaging (NISI) tests in this population remains uncertain. Therefore, this study aims to investigate the value of NISI in risk stratification and predicting cardiac events in patients with low-risk HEART scores (LRHSs).Methods We prospectively included 1384 patients with LRHSs between March 2019 and March 2021. All the patients underwent NISI (involving myocardial perfusion imaging/stress echocardiography). The primary endpoints included cardiac death, non-fatal myocardial infarction and unplanned coronary revascularisation. Secondary endpoints encompassed cardiovascular-related admissions or ED visits.Results The mean patient age was 64±14 years, with 670 (48.4%) being women. During the 634±104 days of follow-up, 58 (4.2%) patients experienced 62 types of primary endpoints, while 60 (4.3%) developed secondary endpoints. Multivariable Cox models, adjusted for clinical and imaging variables, showed that diabetes (HR: 2.38; p=0.008), HEART score of 3 (HR: 1.32; p=0.01), history of coronary artery disease (HR: 2.75; p=0.003), ECG changes (HR: 5.11; p
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