Fatal invasive aspergillosis caused by Aspergillus niger after bilateral lung transplantation

Autor: Enora Atchade, Sylvain Jean-Baptiste, Sandrine Houzé, Claire Chabut, Laurent Massias, Yves Castier, Olivier Brugière, Hervé Mal, Philippe Montravers
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Medical Mycology Case Reports, Vol 17, Iss C, Pp 4-7 (2017)
Druh dokumentu: article
ISSN: 2211-7539
DOI: 10.1016/j.mmcr.2017.05.002
Popis: Aspergillus niger is usually considered to be a low virulence fungus, not commonly reported to cause invasive infections. Invasive pulmonary aspergillosis due to Aspergillus niger was diagnosed in a 43-year-old woman following bilateral lung transplantation. Intravenous voriconazole failed to control progression of the disease. Despite salvage therapy with a combination of voriconazole and caspofungin for 23 days, the patient developed massive hemoptysis leading to death. The authors report the clinical features and treatment of this case.
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