Symptomatic and Subclinical Infection with Rotavirus P[8]G9, Rural Ecuador

Autor: Pablo Endara, Gabriel Trueba, Owen D. Solberg, Sarah J. Bates, Karina Ponce, William Cevallos, Jelle Matthijnssens, Joseph N.S. Eisenberg
Jazyk: angličtina
Rok vydání: 2007
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 13, Iss 4, Pp 574-574 (2007)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid1304.061285
Popis: During the past decade, rotavirus genotype G9 has spread throughout the world, adding to and sometimes supplanting the common genotypes G1–G4. We report evidence of this spread in a population sample within rural Ecuador. A total of 1,656 stool samples were collected from both patients with diarrhea and asymptomatic residents in 22 remote communities in northwestern Ecuador from August 2003 through February 2006. Rotavirus was detected in 23.4% of case-patients and 3.2% of controls. From these 136 rotavirus-positive samples, a subset of 47 were genotyped; 72% were of genotype G9, and 62% were genotype P[8]G9. As a comparison, 29 rotavirus-positive stool samples were collected from a hospital in Quito during March 2006 and genotyped; 86% were of genotype P[8]G9. Few countries have reported P[8]G9 rotavirus detection rates as high as those of the current study. This growing prevalence may require changes to current vaccination programs to include coverage for this genotype.
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