Does ureteral access sheat usage lead to permanent damage in the ureter? A placebo controlled trial in a rabbit model

Autor: Adnan Gücük, Gizem Söyler, Uğur Üyetürk, Burak Yılmaz, İsmail Nalbant, Sebahat Gücük, Aysel Kükner, Ayhan Çetinkaya
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Acta Cirúrgica Brasileira, Vol 33, Iss 5, Pp 408-414 (2018)
Druh dokumentu: article
ISSN: 0102-8650
DOI: 10.1590/s0102-865020180050000002
Popis: Abstract Purpose: To evaluate the clinical stenosis or precursor histological changes that ureteral access sheaths commonly used in ureteroscopic surgeries may cause in the long term in ureter. Methods: In this study, the animals were divided into 9 groups and according to their groups, ureters of the rabbits were endoscopically fitted with 2F and 3F ureter catheters. The catheters were left in place and withdrawn after a specified period of time. All the ureters were excised and evaluated macroscopically, microscopically and histologically. Ureter diameters were measured and FGF-2 (+) labeled fibroblasts were counted in connective tissue as stenosis precursors. Results: Macroscopically or microscopically, no stenosis was found in any group. The ureter diameter of the group that were catheterized for the longest time with the catheter that had the widest diameter was significantly lower than the group with the shorter duration and the catheter with the narrower diameter and the control group. When the groups were compared in terms of their FGF values, there was a significant difference in FGF-2 counts at all three ureter levels (p
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