Investigation the effect of a herbal composition based on blackseed on patients with primary hypothyroidism: A randomized controlled trial

Autor: Najmeh Javidi, Zahra Mazloum Khorasani, Roshanak Salari, Shabnam Niroumand, Mahdi Yousefi
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Avicenna Journal of Phytomedicine, Vol 14, Iss 3, Pp 325-337 (2024)
Druh dokumentu: article
ISSN: 2228-7930
2228-7949
DOI: 10.22038/ajp.2024.23984
Popis: Objective: Hypothyroidism is characterized by insufficient production of thyroxine by the thyroid gland. Levothyroxine may not fully alleviate patients' symptoms. This study aimed to assess the impact of a herbal product on weight, body mass index (BMI), thyroid hormones, lipid profile, fasting blood sugar (FBS), depression, and quality-of-life scores in patients.Materials and Methods: 72 patients with primary hypothyroidism, aged between 20 and 65 years old, participated in the trial and they were randomly allocated into two groups. The intervention group received the herbal powder containing Trachyspermum ammi L., Nigella sativa L., and Citrus aurantifolia L. while the control group received Avicel for 8 weeks.Results: Treatment with the herbal product resulted in statistically significant reductions in anthropometric variables such as BMI (p=0.03), hip circumference (HC) (p=0.008), waist circumference (WC) (p
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