Posttransplant membranous nephropathy - A case report
| Autor: | Shabna Sullaiman, Prabhat Chauhan, Ashwani Kumar, Ritambhra Nada, Ranjana Minz, Vinod Kumar, Ashish Sharma, Sarbpreet Singh, Vivek Kumar, Manish Rathi, Harbir Singh Kohli, Raja Ramachandran |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Indian Journal of Transplantation, Vol 16, Iss 1, Pp 130-134 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2212-0017 2212-0025 |
| DOI: | 10.4103/ijot.ijot_109_21 |
| Popis: | Primary membranous nephropathy (PMN) is a common cause of adult-onset nephrotic syndrome. Anti-M-type phospholipase A2 receptor (PLA2R) antibodies are pathogenic and correlate with clinical outcomes. The role of anti-PLA2R in recurrent PMN is unclear. In the present manuscript, we report five cases of PMN who underwent kidney transplantation (KT) with varying titers of anti-PLA2R pre-kidney transplantation (KT). Two patients with anti-PLA2R in the second and third tertiles had a recurrence of PMN, whereas patients with a negative or anti-PLA2R in the first tertile had no recurrence. The report signals a heightened risk of PMN recurrence in patients with elevated anti-PLA2R antibody titer at KT. |
| Databáze: | Directory of Open Access Journals |
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