| Autor: |
Hai-Bo Wang, Hui-Na Huang, Xin-Bin Chen, Hai-Tang Zhou, Cheng Yuan, Jiao Ou |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
The Microbe, Vol 3, Iss , Pp 100054- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2950-1946 |
| DOI: |
10.1016/j.microb.2024.100054 |
| Popis: |
Tracking the genome diversity and evolution of virus like severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was the hotspot of current researches, which were essential for the developing of prevention strategies and therapeutic vaccines. In the current study, a total of 206073 oral or nasopharyngeal swab specimens were collected in 2022 from entry populations originated from Hong Kong, among which 141 whole genome sequences were obtained through next-generation sequencing and analyzed. Two major Omicron sub-lineages were identified: BA.2.2 (70.21%, 99/141) and BA.5 (24.11% 34/141). An average of 53.22 mutations was emerged in the genome, with S protein and ORF1a harboring the highest number of mutations among structure proteins and non-structure proteins (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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