The effect of vitamin D and magnesium deficiency on the course of adenomyosis in the post covid-19 period in women of reproductive age

Autor: M.B. Zaporozhchenko, A.V. Bulhar, G.F. Stepanov
Jazyk: English<br />Russian<br />Ukrainian
Rok vydání: 2024
Předmět:
Zdroj: Репродуктивная эндокринология, Iss 72, Pp 23-27 (2024)
Druh dokumentu: article
ISSN: 2309-4117
2411-1295
DOI: 10.18370/2309-4117.2024.72.23-27
Popis: Objective of the study: to investigate the content of vitamin D and the trace element magnesium in the blood of women of reproductive age with adenomyosis of the I–II and III–IV degrees after the COVID-19 disease depending on the algorithm of their management at 3, 6 and 12 months, as well as assess the general condition of patients. Materials and methods. 150 women after the COVID-19 disease were under observation: 30 practically healthy women (control group A), 60 patients with adenomyosis of the I–II degree (group B) and 60 patients with adenomyosis of the III–IV degree (group C). Observation continued for 3, 6 and 12 months after the COVID-19 disease. Results. Deterioration of well-being in patients with adenomyosis in the first months after COVID-19 has been proven. The frequency of complaints increased significantly: lethargy (55.0%), headache (36.7%), joint pain (41.7%), muscle pain (40.8%), pelvic pain (38.3%), dyspareunia (100%), etc. According to the scale of verbal assessment of pelvic pain, moderate pain (2 points) was experienced by 30.0% of patients of group B and 43.3% in group C, at the same time, severe (3 points) – 33.3%, very strong (4 points) – 20.0%. A significant decrease in the level of vitamin D and Mg was detected in women after the COVID-19 disease (p < 0.05): in almost all healthy women (group A) and in patients with adenomyosis (groups B and C). A significantly lower content of vitamin D and Mg was found in groups B and C compared to group A (p < 0.05), and in group C compared to group B. The effectiveness of taking vitamin D and magnesium preparations in patients with adenomyosis after the COVID-19 disease was confirmed: a significant difference in the frequency of symptoms characterizing the general condition of patients after 3, 6 and 12 months was obtained: a decrease in the frequency of neuroses, headaches, muscle pain, constant lower abdominal pain, dyspareunia, etc. Conclusions. The effectiveness of taking vitamin D and magnesium preparations by women with adenomyosis after the COVID-19 disease has been confirmed.
Databáze: Directory of Open Access Journals
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