A case of Mantle Cell Lymphoma with Multiple Lymphomatous Polyposis
| Autor: | Seyed Masoud Tabib, Mohammadreza Ravanbod, Seyed Mohammad Valizadeh, Mohammadreza Farzaneh |
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| Jazyk: | English<br />Persian |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Iranian South Medical Journal, Vol 13, Iss 4, Pp 293-298 (2010) |
| Druh dokumentu: | article |
| ISSN: | 1735-4374 1735-6954 |
| Popis: | Multiple Lymphomatous Polyposis (MLP) is characterized by multiple polyps involving long segments of the GI tract. More than 75% of the cases are derived from pregerminal center B cells (mantle zone B cells) & less than 25% from germinal center B cells. Thus MLP is a heterogenous group that includes Mantle Cell Lymphoma (MCL) & Follicular Lymphoma (FL). Here we present a 75-year-old sailor who referred to us with abdominal pain, bloody diarrhea, iron deficiency anemia & lymphadenopathy in inguinal & femoral regions. The presence of intestinal polyposis in colonoscopic & endoscopic evaluations & the pathologic & immunohistochemical findings on tissue specimens that showed B cell lymphoma with moderate proliferative activity (50%) & nodular proliferation of small lymphocytes accompanied with positivity for CD5, CD20, CD43 & negativity for CD3, CD10, CD23 revealed that these findings are consequent to MCL with accompanied MLP. |
| Databáze: | Directory of Open Access Journals |
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