Autor: |
Shengnan Hu, Wenyan Xie, Qiwen Cheng, Xiaoning Zhang, Xiutao Dong, Huaiqi Jing, Jiazheng Wang |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
BMC Microbiology, Vol 23, Iss 1, Pp 1-8 (2023) |
Druh dokumentu: |
article |
ISSN: |
1471-2180 |
DOI: |
10.1186/s12866-023-02913-x |
Popis: |
Abstract Background The increasing incidence and prevalence of carbapenem-resistant Enterobacter cloacae complex (CREC) poses great challenges to infection prevention and disease treatment. However, much remains unknown about the clinical characteristics of CREC isolates. Our objective was to characterize antimicrobial resistance and, carbapenemase production in CREC with 36 CREC isolates collected from a tertiary hospital in Shandong, China. Results Three types of carbapenemases (NDM, IMP and VIM) were detected in these isolates. Among them, NDM carbapenemases were most prevalent, with a 61.2% (22/36) detection rate for NDM-1, 27.8% (10/36) for NDM-5 and 2.8% (1/36) for NDM-7. IMP-4 was found in two isolates and VIM-1 in only one isolate. The MLST analysis identified 12 different sequence types (STs), of which ST171 (27.8%) was the most prevalent, followed by ST418 (25.0%). ST171 isolates had significantly higher rates of resistance than other STs to gentamicin and tobramycin (Ps |
Databáze: |
Directory of Open Access Journals |
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