| Autor: |
Katherine E A Semrau, PhD, Julie Herlihy, MD, Caroline Grogan, MSc, Kebby Musokotwane, MD, Kojo Yeboah-Antwi, MBChB, Reuben Mbewe, MMed, Bowen Banda, MDM, Chipo Mpamba, DipDM, Fern Hamomba, ZRM, Portipher Pilingana, BSc, Andisen Zulu, BA, Pascalina Chanda-Kapata, PhD, Godfrey Biemba, MBChB, Prof. Donald M Thea, MD, William B MacLeod, ScD, Prof. Jonathon L Simon, DSc, Prof. Davidson H Hamer, MD |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
The Lancet Global Health, Vol 4, Iss 11, Pp e827-e836 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2214-109X |
| DOI: |
10.1016/S2214-109X(16)30215-7 |
| Popis: |
Background: Chlorhexidine umbilical cord washes reduce neonatal mortality in south Asian populations with high neonatal mortality rates and predominantly home-based deliveries. No data exist for sub-Saharan African populations with lower neonatal mortality rates or mostly facility-based deliveries. We compared the effect of chlorhexidine with dry cord care on neonatal mortality rates in Zambia. Methods: We undertook a cluster-randomised controlled trial in Southern Province, Zambia, with 90 health facility-based clusters. We enrolled women who were in their second or third trimester of pregnancy, aged at least 15 years, and who would remain in the catchment area for follow-up of 28 days post-partum. Newborn babies received clean dry cord care (control) or topical application of 10 mL of a 4% chlorhexidine solution once per day until 3 days after cord drop (intervention), according to cluster assignment. We used stratified, restricted randomisation to divide clusters into urban or two rural groups (located |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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