Use of Oral Polio Vaccine and the Global Incidence of Mother-to-Child Human Immunodeficiency Virus Transmission

Autor:	Farrokh Habibzadeh, Mahboobeh Yadollahie, Ashraf Simi
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	HIV acquired immunodeficiency syndrome vertical transmission of infectious disease oral poliovirus vaccine cross protection innate immunity Public aspects of medicine RA1-1270
Zdroj:	Frontiers in Public Health, Vol 10 (2022)
Druh dokumentu:	article
ISSN:	2296-2565
DOI:	10.3389/fpubh.2022.878298
Popis:	BackgroundMother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) is an important global health issue. We hypothesized that the live attenuated poliovirus existing in oral polio vaccine (OPV) may protect uninfected neonates born to HIV-positive mothers through the stimulation of innate immune system.ObjectiveTo test the hypothesis that countries using OPV have a lower MTCT rate (due to postnatal protection provided by the vaccine) compared with those using only inactivated polio vaccine (IPV).MethodsIn an ecological study, the incidence of HIV/AIDS in children aged
Databáze:	Directory of Open Access Journals
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