Evaluation of antibacterial efficacy of garlic (Allium sativum) and ginger (Zingiber officinale) crude extract against multidrug-resistant (MDR) poultry pathogen

Autor: Zakaria Al Noman, Tasnia Tabassum Anika, Sabbya Sachi, Jannatul Ferdous, Yousuf Ali Sarker, Md. Abdus Sabur, Md. Tanvir Rahman, Mahmudul Hasan Sikder
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Advanced Veterinary and Animal Research, Vol 10, Iss 2, Pp 151-156 (2023)
Druh dokumentu: article
ISSN: 2311-7710
DOI: 10.5455/javar.2023.j664
Popis: Objective: The study is aimed to understand the antibacterial sensitivity of native and Indian varieties of garlic (Allium sativum) and ginger (Zingiber officinale) crude extracts against multi¬drug-resistant (MDR) poultry pathogen (Escherichia coli and Salmonella sp.). Materials and Methods: Thin layer chromatography (TLC) is used to identify the target spices' bioactive antibacterial compounds. MDR E. coli and Salmonella sp. were isolated from poultry. The TLC-Bioautography technique was applied to explore the antibacterial potentiality of garlic and ginger. Results: Inhibitory activities of garlic were Zone of inhibition (ZI) = 14.03 ± 0.15 mm and 19.70 ± 0.36 mm, Minimum inhibitory concentration (MIC): 0.625 and 0.325 mg/ml, and ginger were ZI = 14.63 ± 0.30 mm and 11.56 ± 0.51mm, MIC: 9.0 mg/ml against E. coli and Salmonella sp., respec¬tively. Two bands of garlic (Rf value = 0.31 and 0.50) and one band of ginger (Rf value = 0.71) showed inhibitory potential in TLC-Bioautography against both MDR isolates. Conclusion: Garlic and ginger were effective against MDR E. coli and Salmonella sp. These spices could be a suitable alternative during the antibiotic void. [J Adv Vet Anim Res 2023; 10(2.000): 151-156]
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