Antibiotic Prescribing Patterns at COVID-19 Dedicated Wards in Bangladesh: Findings from a Single Center Study

Autor: Md. Maruf Ahmed Molla, Mahmuda Yeasmin, Md. Khairul Islam, Md. Mohiuddin Sharif, Md. Robed Amin, Tasnim Nafisa, Asish Kumar Ghosh, Monira Parveen, Md. Masum Hossain Arif, Junaid Abdullah Jamiul Alam, Syed Jafar Raza Rizvi, K.M. Saif-Ur-Rahman, Arifa Akram, A.K.M. Shamsuzzaman
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Infection Prevention in Practice, Vol 3, Iss 2, Pp 100134- (2021)
Druh dokumentu: article
ISSN: 2590-0889
DOI: 10.1016/j.infpip.2021.100134
Popis: Summary: Background: As evidence is mounting regarding irrational and often unnecessary use of antibiotics during the COVID-19 pandemic a cross-sectional Point Prevalence Survey (PPS) (in accordance with WHO guideline) was conducted across COVID-19 dedicated wards in Dhaka Medical College and Hospital (DMCH). Methodology: Antibiotic usage data were collected from 193 patients at different COVID-19 dedicated wards at DMCH on 11 June 2020. Comparisons in antibiotic usage were made between different groups using Pearson chi-square and Fisher's exact test. Result: Findings reveal all surveyed patients (100%) were receiving at least one antibiotic with 133 patients (68.91%) receiving multiple antibiotics. Overall, patients presenting with the severe disease received more antibiotics. Third-generation cephalosporins (i.e. ceftriaxone) (53.8%), meropenem (40.9%), moxifloxacin (29.5%), and doxycycline (25.4%) were the four most prescribed antibiotics among surveyed patients. Diabetes mellitus (DM) was independently associated with multiple antibiotic prescribing. Abnormal C-reactive protein (CRP) and serum d-dimer were linked with higher odds of multiple antibiotic prescribing among study patients. Conclusion: Prevalence of multiple antibiotic prescriptions was high among severely ill patients and those with abnormal CRP and d-dimer levels. Data regarding the quality of antibiotic prescribing were lacking.
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