A Surface Plasmon Resonance Histamine Sensor Based on an Electropolymerized Molecularly Imprinted Polymer (E-MIP)
| Autor: | Hubilla Frances Adeline D., Mabilangan Arvin I., Advincula Rigoberto C., del Mundo Florian R. |
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| Jazyk: | English<br />French |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | MATEC Web of Conferences, Vol 95, p 02006 (2017) |
| Druh dokumentu: | article |
| ISSN: | 2261-236X 20179502 |
| DOI: | 10.1051/matecconf/20179502006 |
| Popis: | In this paper, histamine sensing by surface plasmon resonance (SPR) spectroscopy using an electropolymerized molecularly imprinted polymer (E-MIP) of functionalized polyterthiophene and histamine is reported. The MIP histamine sensor showed good linear relationship (R2 = 0.995) between the SPR angle shift and the logarithm of histamine concentration, ranging from 15 – 500 μg/mL, with a limit of detection (LOD) of 2.0 μg/mL and a calibration sensitivity of 44.6 m° per log μg/mL histamine. Results also showed higher binding affinity of histamine for the MIP sensor than for the non-imprinted (NIP) sensor indicating excellent specificity. Moreover, the selectivity of the MIP histamine sensor against some of its structural analogues was demonstrated. |
| Databáze: | Directory of Open Access Journals |
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