Autor: |
Bongyoung Kim, Jeoungyeon Kim, Hyun-uk Jo, Ki Tae Kwon, Seong-yeol Ryu, Seong-Heon Wie, Jieun Kim, Se Yoon Park, Kyung-Wook Hong, Hye In Kim, Hyun ah Kim, Mi-Hee Kim, Mi Hyun Bae, Yong-Hak Sohn, Yangsoon Lee, Hyunjoo Pai |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Journal of Microbiology, Immunology and Infection, Vol 55, Iss 4, Pp 678-685 (2022) |
Druh dokumentu: |
article |
ISSN: |
1684-1182 |
DOI: |
10.1016/j.jmii.2022.01.001 |
Popis: |
Purpose: This study aimed to examine the changes in the characteristics of community-onset fluoroquinolone-resistant (FQ-R) Escherichia coli isolates causing community-acquired acute pyelonephritis (APN) in South Korea. Methods: Blood or urine samples were prospectively collected from patients aged ≥15 years with community-acquired APN who were admitted to one of the eight Korean hospitals included in this study between September 2017 and August 2018. Phylogenetic typing, multilocus sequence typing, and molecular characterization of β-lactamase resistance and plasmid-mediated quinolone resistance (PMQR) determinants were performed. The data were compared with those from a previous study with the same design conducted in 2010–2011. Results: A total of 300 and 346 isolates were identified in 2010–2011 and 2017–2018, respectively. Among them, 76 (22.0%) and 77 (25.7%) FQ-R isolates were identified in 2010–2011 and 2017–2018, respectively. A significantly higher antimicrobial resistance against third-to fourth-generation cephalosporins, including cefotaxime (23.9% vs. 77.9%, P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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