| Autor: |
Aatreya Chakravarti, Amin Hazrati Marangalou, Ian Matthew Costanzo, Devdip Sen, Mirco Sciulli, Yusuke Tsuno, Ulkuhan Guler |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Micromachines, Vol 13, Iss 5, p 727 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2072-666X |
| DOI: |
10.3390/mi13050727 |
| Popis: |
Visualizing neuronal activation and neurotransmitter release by using fluorescent sensors is increasingly popular. The main drawback of contemporary multi-color or multi-region fiber photometry systems is the tethered structure that prevents the free movement of the animals. Although wireless photometry devices exist, a review of literature has shown that these devices can only optically stimulate or excite with a single wavelength simultaneously, and the lifetime of the battery is short. To tackle this limitation, we present a prototype for implementing a fully wireless photometry system with multi-color and multi-region functions. This paper introduces an integrated circuit (IC) prototype fabricated in TSMC 180 nm CMOS process technology. The prototype includes 3-channel optical excitation, 2-channel optical recording, wireless power transfer, and wireless data telemetry blocks. The recording front end has an average gain of 107 dB and consumes 620 μW of power. The light-emitting diode (LED) driver block provides a peak current of 20 mA for optical excitation. The rectifier, the core of the wireless power transmission, operates with 63% power conversion efficiency at 13.56 MHz and a maximum of 87% at 2 MHz. The system is validated in a laboratory bench test environment and compared with state-of-the-art technologies. The optical excitation and recording front end and the wireless power transfer circuit evaluated in this paper will form the basis for a future miniaturized final device with a shank that can be used in in vivo experiments. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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