Impact of Rap-Phr system abundance on adaptation of Bacillus subtilis

Autor: Ramses Gallegos-Monterrosa, Mathilde Nordgaard Christensen, Tino Barchewitz, Sonja Koppenhöfer, B. Priyadarshini, Balázs Bálint, Gergely Maróti, Paul J. Kempen, Anna Dragoš, Ákos T. Kovács
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-021-01983-9
Popis: Ramses Gallegos-Monterrosa, Mathilde Nordgaard Christensen, and colleagues investigate how a single or double deletion of the rap-phr genes, parts of peptide-based quorum sensing systems, impacts the sporulation and biofilm formation of B. subtilis under four different conditions and a multitude of strains. Using strain-specific barcoding and complete genome sequencing, the authors show that competitive selection is driven by acquired mutations, and that selected strains demonstrate increased spore fitness relative to their ancestors and wild types.
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