Impact of rural residence on the presentation, management and survival of patients with non-metastatic muscle-invasive bladder carcinoma

Autor: Furkan Dursun, Ahmed Elshabrawy, Hanzhang Wang, Dharam Kaushik, Michael A. Liss, Robert S. Svatek, John L. Gore, Ahmed M. Mansour
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Investigative and Clinical Urology, Vol 64, Iss 6, Pp 561-571 (2023)
Druh dokumentu: article
ISSN: 20230125
2466-0493
2466-054X
DOI: 10.4111/icu.20230125
Popis: Purpose: To assess the impact of rural and remote residence on the receipt of guidelines-recommended treatment, quality of treatment and overall survival (OS) in patients with non-metastatic muscle-invasive bladder cancer (MIBC). Materials and Methods: Patients with MIBC were identified using National Cancer Database. Patients were classified into three residential areas. Logistic regression models were used to assess associations between geographic residence and receipt of radical cystectomy (RC) or chemoradiation therapy (CRT). Models were fitted to assess quality benchmarks of RC and CRT. Results: We identified 71,395 patients. Of those 58,874 (82.5%) were living in Metro areas, 8,534 (11.9%) in urban-rural adjacent (URA), and 3,987 (5.6%) in urban-rural remote to metro area (URR). URR residence was significantly associated with poor OS compared to URA and Metro residence (HR 0.87, 95% CI 0.81–0.94 and HR 0.90, 95% CI 0.87–0.93, p
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