The prognostic value of the Glasgow coma scale, serum acetylcholinesterase and leukocyte levels in acute organophosphorus poisoning

Autor: Cander Basar, Dur Ali, Yildiz Mesut, Koyuncu Feridun, Girisgin Abdullah, Gul Mehmet, Okumus Mehmet
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Annals of Saudi Medicine, Vol 31, Iss 2, Pp 163-166 (2011)
Druh dokumentu: article
ISSN: 0256-4947
0975-4466
Popis: Background and Objectives: Organophosphate poisoning (OP) is a serious clinical condition that may sometimes be fatal. The aim of this study was to determine whether the Glasgow coma scale (GCS), and serum acetylcholinesterase and leukocyte levels have prognostic value in acute OP poisoning. Design and Setting: Retrospective review of records of patients admitted to the intensive care unit of Selcuk University, Meram Medical Faculty, Emergency Department, Konya, Turkey, between January 2006 and January 2009. Methods: We studied acutely OP-poisoned patients admitted within 24 hours after OP exposure. Results: The mean age of the 25 patients was 37 years (range, 20-80 years). Three (12%) of the 25 patients (male-female ratio, 12:13) died. The mean GCS values of the patients who died were significantly lower compared to those of the group that survived (4 vs 11.7, respectively PConclusion: Although serum cholinesterase values can be used in the quick diagnosis, their efficiency at predicting outcome in patients with OP poisoning has not been established. It has also been determined that serum leukocyte values have no prognostic value in OP poisoning, but GCS values have been found to be effective in predicting the outcome.
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