The effect of carbodiimide on push-out bond strength of fiber posts and endogenous enzymatic activity

Autor: Uros Josic, Claudia Mazzitelli, Tatjana Maravic, Allegra Comba, Milena Cadenaro, Ivana Radovic, Maicon Sebold, Gianluca Turco, Lorenzo Breschi, Annalisa Mazzoni
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Oral Health, Vol 23, Iss 1, Pp 1-12 (2023)
Druh dokumentu: article
ISSN: 1472-6831
DOI: 10.1186/s12903-023-03067-y
Popis: Abstract Background To investigate the effect of 0.3 M 1-ethyl-3(3-dimethylaminopropyl) carbodiimide (EDC) aqueous solution pretreatment on push-out bond strength (PBS) and matrix-metalloproteinases (MMPs) activity within radicular dentin when different post cementation strategies were employed. Methods One hundred and twenty monoradicular human teeth were endodontically treated and randomly divided into six groups, depending on the cementation strategy and root dentin pretreatment (n = 20): EAR: cementation with an etch-and-rinse adhesive (LuxaBond Total Etch, DMG) and resin cement (LuxaCore Z Dual, DMG); EAR/EDC: 1 min EDC pretreatment after etching + EAR; SE: cementation with a self-etch primer (Multilink Primer, Ivoclar Vivadent) and corresponding cement (Multilink Automix, Ivoclar Vivadent); SE/EDC: self-etch primer + EDC pretreatment + SE; SA: cementation with a universal self-adhesive cement (RelyX Universal, 3 M); SA/EDC: EDC pretreatment + SA. Slices were submitted to PBS test and interfacial nanoleakage evaluation 24 h after cementation or after thermocycling (40.000 cycles, 5–55 °C). To investigate the effect of EDC on MMPs activity, 4 additional first maxillary premolars per group were processed for in situ zymography analysis. Multivariate ANOVA and post hoc Tukey tests were used to analyze PBS values. The data from in situ zymography were analyzed with Kruskal-Wallis test and Dunn’s pairwise multiple comparison procedures (α = 0.05). Results The variables “EDC pretreatment”, “root region” and “thermocycling” significantly influenced PBS (p 0.05). Thermocycling significantly reduced PBS in SE and SA groups (p
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