Effects of Sacha Inchi Leaf Alcohol Extract on Delaying Aging of Caenorhabditis elegans

Autor: Yuping LAI, Yingyi CHEN, Wanping WEI, Miaoqing AN, Zebin ZOU, Bing DU, Pan LI
Jazyk: čínština
Rok vydání: 2023
Předmět:
Zdroj: Shipin gongye ke-ji, Vol 44, Iss 21, Pp 402-411 (2023)
Druh dokumentu: article
ISSN: 1002-0306
DOI: 10.13386/j.issn1002-0306.2023020176
Popis: In this study, the effects of different mass concentrations (5, 10 and 15 mg/mL) of Sacha inchi leaf alcohol extract (SILAE) on Caenorhabditis elegans (C. elegans) longevity, mobility, reproductive capacity, resistance to oxidative stress and levels of ROS, lipofuscin and malondialdehyde (MDA) in vivo, as well as the effects of SILAE on enzymatic and non-enzymatic antioxidants in C. elegans were investigated by constructing a senescence model of C. elegans, with the aim of providing certain theoretical references to the further research and application of Sacha inchi leaf. The results showed that SILAE at 5 and 10 mg/mL significantly prolonged the life span of C. elegans compared with the blank group (P
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