The improvement effect of apple cider vinegar as a functional food on anthropometric indices, blood glucose and lipid profile in diabetic patients: a randomized controlled clinical trial

Autor: Sima Jafarirad, Mohammad-Reza Elahi, Anahita Mansoori, Abdollah Khanzadeh, Mohammad-Hossein Haghighizadeh
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Clinical Diabetes and Healthcare, Vol 4 (2023)
Druh dokumentu: article
ISSN: 2673-6616
DOI: 10.3389/fcdhc.2023.1288786
Popis: BackgroundNumerous medical costs are spent each year on treating and preventing the progression of diabetes. The positive effect of apple cider vinegar (ACV) has been shown on post-prandial hyperglycemia. This study aimed to evaluate the effects of prolonged consumption of ACV on blood glucose indices and lipid profile in patients with type 2 diabetes.MethodsThis study was a randomized clinical trial and the participants were adults with type 2 diabetes. Participants were divided into two groups: ACV and control. The ACV group was treated with 30 ml of ACV per day. Both the intervention and control groups received the same recommendation for a healthy diet. Before and after eight weeks, fasting blood glucose, insulin, hemoglobin A1C, insulin resistance, total cholesterol (Chol), low-density lipoprotein (LDL), high-density lipoprotein (HDL) and triglyceride were measured.ResultsFasting blood glucose decreased after intervention in both groups, which was only significant in the ACV group (p = 0.01). There was a significant difference in hemoglobin A1C levels between the two groups (p < 0.001) after eight weeks. LDL was decreased in the ACV group (p < 0.001). Total Chol, LDL/HDL and Chol/HDL ratio decreased after the intervention period in the ACV group compared to the control group (p = 0.003, p = 0.001 and p = 0.001, respectively).ConclusionDaily consumption of ACV may have beneficial effects in controlling blood glucose indices and lipid profile in patients with type 2 diabetes.Clinical trial registrationhttp://www.irct.ir, identifier IRCT20140107016123N13.
Databáze: Directory of Open Access Journals