| Autor: |
Jinghui Guo, Fang Fang, Qiuting Dai, Wenxin Zhang, Weihao Di, Jiaan Hu, Jian Zhao, Jiumei Cao, Ying Wang |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Stem Cell Research, Vol 52, Iss , Pp 102186- (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1873-5061 |
| DOI: |
10.1016/j.scr.2021.102186 |
| Popis: |
As the global median population age increases, neurological diseases associated with aging pose significant challenges to human health. Appropriate modeling systems can be useful tools to better understand the mechanism of age-related neuronal degeneration diseases. Here, we successfully generated an iPSC-derived modeling system of an 82-year-old healthy man, this newly established line showed that all pluripotent markers were expressed, and the differentiation potential was confirmed by trilineage differentiation. STR profiling proved the cell line identity, and G-binding showed the normal karyotype. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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