Is point-of-care accurate for indicating thrombolysis in anticoagulated patients on oral anticoagulation treatments?
| Autor: | Tatiana P. Bruch, Danielle C. Mendes, Jeff C. Pedrozo, Lívia Figueiredo, Edison M. Nóvak, Viviane F. Zétola, Marcos C. Lange |
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| Jazyk: | angličtina |
| Předmět: | |
| Zdroj: | Arquivos de Neuro-Psiquiatria, Vol 72, Iss 7, Pp 487-489 |
| Druh dokumentu: | article |
| ISSN: | 1678-4227 0004-282X |
| DOI: | 10.1590/0004-282X20140075 |
| Popis: | The use of oral anticoagulation treatment (OAT) in patients with an international normalized ratio (INR) higher than 1.7 is a contraindication to thrombolysis in acute ischemic stroke. The aim of the present study is to compare the use of point-of-care (POC) coagulometers to the standard coagulation analysis (SCA) procedure of the INR as a decision-making test for use with patients taking OAT. Method: Eighty patients on chronic OAT underwent a POC and an SCA during a regular outpatient evaluation. Results: When comparing the abilities of the POC test and the SCA test to identify adequate levels for thrombolysis (≤1.7), the POC had a sensitivity of 96.6% (95%CI 88.4-99.1) and a specificity of 60.0% (95%CI 38.6-78). POC overestimated INR levels by 0.51 points compared to the SCA test. Conclusion: POC has a high sensitivity compared to the SCA test for the identification of patients within the cut-off point for thrombolysis. |
| Databáze: | Directory of Open Access Journals |
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