CLINICAL DIAGNOSTIC VALUE OF AUTOANTIBODIES IN THE DIAGNOSIS OF AUTOIMMUNE LIVER DISEASES
Autor: | V. V. Bazarnyi, E. Yu. Mikhailova, E. A. Partylova |
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Jazyk: | ruština |
Rok vydání: | 2015 |
Předmět: | |
Zdroj: | Медицинская иммунология, Vol 17, Iss 1, Pp 93-96 (2015) |
Druh dokumentu: | article |
ISSN: | 1563-0625 2313-741X |
DOI: | 10.15789/1563-0625-2015-1-93-96 |
Popis: | We are studied the 15 patients with autoimmune liver diseases and 36 patients without autoimmune pathology found the diagnostic value of antinuclear and antimitochondrial autoantibodies (AMA-M2) tests, and antibodies to asialoglycoprotein receptor (anti-ASGPR). Based on the ROC analysis showed that the diagnostic sensitivity and diagnostic specificity of AMA-M2 was 73% and 100% and for anti-ASGPR – 60% and 77%, respectively. Therefore, the test for anti-ASGPR in autoimmune diseases of the liver showed no advantages over standart tests, and its using in clinical practice requires clarification. |
Databáze: | Directory of Open Access Journals |
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