CLINICAL DIAGNOSTIC VALUE OF AUTOANTIBODIES IN THE DIAGNOSIS OF AUTOIMMUNE LIVER DISEASES

Autor: V. V. Bazarnyi, E. Yu. Mikhailova, E. A. Partylova
Jazyk: ruština
Rok vydání: 2015
Předmět:
Zdroj: Медицинская иммунология, Vol 17, Iss 1, Pp 93-96 (2015)
Druh dokumentu: article
ISSN: 1563-0625
2313-741X
DOI: 10.15789/1563-0625-2015-1-93-96
Popis: We are studied the 15 patients with autoimmune liver diseases and 36 patients without autoimmune pathology found the diagnostic value of antinuclear and antimitochondrial autoantibodies (AMA-M2) tests, and antibodies to asialoglycoprotein receptor (anti-ASGPR). Based on the ROC analysis showed that the diagnostic sensitivity and diagnostic specificity of AMA-M2 was 73% and 100% and for anti-ASGPR – 60% and 77%, respectively. Therefore, the test for anti-ASGPR in autoimmune diseases of the liver showed no advantages over standart tests, and its using in clinical practice requires clarification.
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