| Autor: |
Boitumelo Prescilla Letswalo, Karin Schmid-Zalaudek, Bianca Brix, Edna Ngoakoana Matjuda, Fabian Klosz, Natalie Obernhumer, Michael Gaisl, Godwill Azeh Engwa, Constance Sewani-Rusike, Per Morten Fredriksen, Benedicta Nkeh-Chungag, Nandu Goswami |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
BMJ Open, Vol 11, Iss 3 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2044-6055 |
| DOI: |
10.1136/bmjopen-2020-042955 |
| Popis: |
Objectives Prevalence of child and adolescents’ overweight and obesity in low- and middle-income countries has increased dramatically. Simultaneously, the incidence of pre-hypertension/hypertension is also increasing in children, which, in turn, predisposes these children to the risk of cardiovascular disease (CVD) in later life. The present study assessed cardiometabolic risk factors and early indicators of vascular dysfunction in adolescents from a low socio-economic rural area in South Africa.Design Cross-sectional cohort study.Setting The study was conducted in public schools in Mthatha, OR Tambo district municipality, Eastern Cape Province, South Africa.Participants A total of 244 adolescents (188 females) of African ancestry aged 13–16 years were enrolled.Primary and secondary outcome measures Anthropometric and haemodynamic measures and pulse wave velocity (PWV) were related to overweight/obesity and hypertension. Blood markers of cardiometabolic syndrome were assessed as well as vascular function (via PWV).Results One-third (33.0%) of the adolescents exceeded the age and sex-specific body mass index percentiles for overweight (≥85th) or obesity (>95th) with a prevalence of 61.1% pre-hypertensives in this group. Overweight/obesity and hypertension were associated with higher triglycerides (lean:overweight: 0.794.69 mmol/L, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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